CHEM 407: Applied Biochemistry: (4) (F;S)
This application-oriented course will review the chemistry of macromolecules in living systems, with emphasis on biotechnological and biomedical methods. The first part of the course will focus on the relationship between the chemistry, structure and function of proteins, nucleic acids, carbohydrates, lipids, and membranes. Critical methods used in modern biochemistry to analyze macromolecules in biotechnological, biomedical and research interests will be covered. The final topics will be concerned with informational biochemistry, DNA replication, DNA recombinant technology and cloning methods, transcription factors analysis, sequencing techniques (DNA and protein), microarrays and SiRNA. Extensive use of the Internet's resources (Pubmed etc.) and on-line journals will be also expected. This approach will assist the student to make the connection between abstract ideas and concrete applications.